A multicentre study on spontaneous in-cage activity and micro-environmental conditions of IVC housed C57BL/6J mice during consecutive cycles of bi-weekly cage-change

Mice respond to a cage change (CC) with altered activity, disrupted sleep and increased anxiety. A bi-weekly cage change is, therefore, preferred over a shorter CC interval and is currently the prevailing routine for Individually ventilated cages (IVCs). However, the build-up of ammonia (NH3) during...

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Bibliographic Details
Main Authors: B. Ulfhake, H. Lerat, J. Honetschlager, K. Pernold, M. Rynekrová, K. Escot, C. Recordati, R. V. Kuiper, G. Rosati, M. Rigamonti, S. Zordan, J.-B. Prins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132304/?tool=EBI