Fostemsavir resistance-associated polymorphisms in HIV-1 subtype C in a large cohort of treatment-naïve and treatment-experienced individuals in Botswana

Fostemsavir resistance-associated polymorphisms in HIV-1 subtype C in a large cohort of treatment-naïve and treatment-experienced individuals in Botswana

ABSTRACT There are limited data on the prevalence of fostemsavir (FTR) resistance-associated polymorphisms in people with HIV in Botswana. We sought to determine the prevalence of FTR resistance-associated polymorphisms in HIV-1 subtype C sequences from antiretroviral therapy (ART)-naïve and ART-exp...

Полное описание

Библиографические подробности
Главные авторы: Boitumelo J. L. Zuze, Botshelo T. Radibe, Wonderful T. Choga, Ontlametse T. Bareng, Natasha O. Moraka, Dorcas Maruapula, Kedumetse Seru, Patrick Mokgethi, Baitshepi Mokaleng, Nokuthula Ndlovu, Nametso Kelentse, Molly Pretorius-Holme, Roger Shapiro, Shahin Lockman, Joseph Makhema, Vlad Novitsky, Kaelo K. Seatla, Sikhulile Moyo, Simani Gaseitsiwe
Формат: Статья
Язык:English
Опубликовано: American Society for Microbiology 2023-12-01
Серии:Microbiology Spectrum
Предметы:
HIV-1 C
entry inhibitors
fostemsavir (FTR)
drug-resistant mutations (DRMs)
polymorphisms
Botswana
Online-ссылка:https://journals.asm.org/doi/10.1128/spectrum.01251-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01251-23

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