Possible Involvement of Hsp90 in the Regulation of Telomere Length and Telomerase Activity During the Leishmania amazonensis Developmental Cycle and Population Proliferation

Possible Involvement of Hsp90 in the Regulation of Telomere Length and Telomerase Activity During the Leishmania amazonensis Developmental Cycle and Population Proliferation

The Leishmania developmental cycle comprises three main life forms in two hosts, indicating that the parasite is continually challenged due to drastic environmental changes. The disruption of this cycle is critical for discovering new therapies to eradicate leishmaniasis, a neglected disease that af...

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Bibliographic Details
Main Authors: Beatriz C. D. de Oliveira, Mark E. Shiburah, Stephany C. Paiva, Marina R. Vieira, Edna Gicela O. Morea, Marcelo Santos da Silva, Cristiane de Santis Alves, Marcela Segatto, Fernanda Gutierrez-Rodrigues, Júlio C. Borges, Rodrigo T. Calado, Maria Isabel N. Cano
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Leishmania life forms
continuous in vitro passages
telomeres maintenance
telomerase ribonucleoprotein complex
LHsp90
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.713415/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.713415/full

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