Ultrasound-assisted continuous crystallization of metastable polymorphic pharmaceutical in a slug-flow tubular crystallizer

Metastable polymorphic pharmaceuticals have garnered significant attention in recent years due to their enhanced physicochemical properties, including solubility, bioavailability, and intellectual property considerations. However, the manufacturing of metastable form pharmaceuticals remains a formid...

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Bibliographic Details
Main Authors: Huadong Liao, Wenfeng Huang, Ling Zhou, Lan Fang, Zhenguo Gao, Qiuxiang Yin
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Ultrasonics Sonochemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1350417723003395