Succinum extracts inhibit microglial-derived neuroinflammation and depressive-like behaviors

Microglia are emerging as important targets for the treatment of neuropsychiatric disorders. The phagocytic microglial phenotype and the resulting neuroinflammation lead to synaptic loss and neuronal cell death. To explore potential candidates that inhibit microglial hyperactivation, we first invest...

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Bibliographic Details
Main Authors: Ji-Yun Kang, Dong-Cheol Baek, Chang-Gue Son, Jin-Seok Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.991243/full