Optimizing expression quantitative trait locus mapping workflows for single-cell studies
Abstract Background Single-cell RNA sequencing (scRNA-seq) has enabled the unbiased, high-throughput quantification of gene expression specific to cell types and states. With the cost of scRNA-seq decreasing and techniques for sample multiplexing improving, population-scale scRNA-seq, and thus singl...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-021-02407-x |