Clonal evolution of AML1-ETO coexisting with BCR-ABL and additional chromosome abnormalities in a blastic transformation of chronic myeloid leukemia

Blast crisis develops in a minority of patients with chronic myeloid leukemia even in the era of tyrosine kinase inhibitor (TKI) therapy. Reports suggest that we know little about the mechanism of BCR-ABL and AML1-ETO co-expression in blast crisis of chronic myeloid leukemia, and that other chromoso...

Full description

Bibliographic Details
Main Authors: Cheng-Cheng Ma, Ye Chai, Hui ling Chen, Xin Wang, Ying Gao, Wan li Hu, Xue Xiang
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520919237