DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium

DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium

Abstract The pathophysiological mechanisms of postoperative delirium (POD) are still not clear, and no reliable biomarker is available to differentiate those with and without POD. Pre- and post-surgery blood from epilepsy subjects undergoing neurosurgery were collected. DNA methylation (DNAm) levels...

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Bibliographic Details
Main Authors: Takehiko Yamanashi, Takaaki Nagao, Nadia E. Wahba, Pedro S. Marra, Kaitlyn J. Crutchley, Alissa A. Meyer, Ally J. Andreasen, Mandy M. Hellman, Sydney S. Jellison, Christopher G. Hughes, Pratik P. Pandharipande, Matthew A. Howard, III, Hiroto Kawasaki, Masaaki Iwata, Marco M. Hefti, Gen Shinozaki
Format: Article
Language:English
Published: Nature Publishing Group 2021-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01752-6

Internet

https://doi.org/10.1038/s41398-021-01752-6

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