Reducing glutamic acid decarboxylase in the dorsal dentate gyrus attenuates juvenile stress induced emotional and cognitive deficits

Reducing glutamic acid decarboxylase in the dorsal dentate gyrus attenuates juvenile stress induced emotional and cognitive deficits

A high degree of regional, temporal and molecular specificity is evident in the regulation of GABAergic signaling in stress-responsive circuitry, hampering the use of systemic GABAergic modulators for the treatment of stress-related psychopathology. Here we investigated the effectiveness of local in...

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Bibliographic Details
Main Authors: Kuldeep Tripathi, Yunus Emre Demiray, Stefanie Kliche, Liang Jing, Somoday Hazra, Joyeeta Dutta Hazra, Gal Richter-Levin, Oliver Stork
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
Subjects:
PTSD
GABA
GAD65
GAD67
Dentate gyrus
Stress resilience
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521000588

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http://www.sciencedirect.com/science/article/pii/S2352289521000588

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