SART3-Dependent Accumulation of Incomplete Spliceosomal snRNPs in Cajal Bodies

Cajal bodies (CBs) are evolutionarily conserved nuclear structures involved in the metabolism of spliceosomal small nuclear ribonucleoprotein particles (snRNPs). CBs are not present in all cell types, and the trigger for their formation is not yet known. Here, we depleted cells of factors required f...

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Bibliographic Details
Main Authors: Ivan Novotný, Anna Malinová, Eva Stejskalová, Daniel Matějů, Klára Klimešová, Adriana Roithová, Martin Švéda, Zdeněk Knejzlík, David Staněk
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714010596