Simultaneous analysis of multiple steroidal biomarkers in saliva for objective stress assessment by on-line coupling of automated in-tube solid-phase microextraction and polarity-switching LC-MS/MS

Simultaneous analysis of multiple steroidal biomarkers in saliva for objective stress assessment by on-line coupling of automated in-tube solid-phase microextraction and polarity-switching LC-MS/MS

To objectively and quantitatively assess the degree of stress, we developed a simple and sensitive method for the simultaneous determination of four steroidal stress biomarkers in saliva: cortisol (CRT), testosterone (TES), dehydroepiandrosterone (DHEA) and DHEA sulfate (DHAES), by on-line coupling...

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Bibliographic Details
Main Authors: Hiroyuki Kataoka, Hayata Ohshima, Taishi Ohkawa
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Talanta Open
Subjects:
Cortisol
Stress biomarkers
Saliva
In-tube solid-phase microextraction
Polarity-switching
LC-MS/MS
Online Access:http://www.sciencedirect.com/science/article/pii/S2666831922000947

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http://www.sciencedirect.com/science/article/pii/S2666831922000947

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