Partial genome content within rAAVs impacts performance in a cell assay-dependent manner
Recombinant adeno-associated viruses (rAAVs) deliver DNA to numerous cell types. However, packaging of partial genomes into the rAAV capsid is of concern. Although empty rAAV capsids are studied, there is little information regarding the impact of partial DNA content on rAAV performance in controlle...
Main Authors: | Bryan Troxell, Sarah L. Jaslow, I-Wei Tsai, Chelsea Sullivan, Benjamin E. Draper, Martin F. Jarrold, Kate Lindsey, Levi Blue |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050123001092 |
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