Essential metabolism for a minimal cell

Essential metabolism for a minimal cell

JCVI-syn3A, a robust minimal cell with a 543 kbp genome and 493 genes, provides a versatile platform to study the basics of life. Using the vast amount of experimental information available on its precursor, Mycoplasma mycoides capri, we assembled a near-complete metabolic network with 98% of enzyma...

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Bibliographic Details
Main Authors: Marian Breuer, Tyler M Earnest, Chuck Merryman, Kim S Wise, Lijie Sun, Michaela R Lynott, Clyde A Hutchison, Hamilton O Smith, John D Lapek, David J Gonzalez, Valérie de Crécy-Lagard, Drago Haas, Andrew D Hanson, Piyush Labhsetwar, John I Glass, Zaida Luthey-Schulten
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
JCVI-syn3A
metabolic reconstruction
transposon mutagenesis
mycoplasma
proteomics
gene essentiality
Online Access:https://elifesciences.org/articles/36842

Internet

https://elifesciences.org/articles/36842

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