Integrated Transcriptomic and Epigenetic Study of PCOS: Impact of Map3k1 and Map1lc3a Promoter Methylation on Autophagy

Integrated Transcriptomic and Epigenetic Study of PCOS: Impact of Map3k1 and Map1lc3a Promoter Methylation on Autophagy

Polycystic ovary syndrome (PCOS) is a prevalent heterogeneous endocrine and metabolic disorder in women of reproductive age. Epigenetic mechanisms contribute to the development of PCOS. Nevertheless, the role of DNA methylation in the development of PCOS remains unclear. To investigate the molecular...

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Bibliographic Details
Main Authors: Yulan Qin, Ting Li, Hui Zhao, Zhanrui Mao, Chunxia Ding, Yani Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
polycystic ovary syndrome
PNA mice
DNA methylation
MAPK pathway
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.620241/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.620241/full

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