Identification of ST3GAL5 as a prognostic biomarker correlating with CD8+ T cell exhaustion in clear cell renal cell carcinoma

Identification of ST3GAL5 as a prognostic biomarker correlating with CD8+ T cell exhaustion in clear cell renal cell carcinoma

Aberrant sialylation is frequently observed in tumor development, but which sialyltransferases are involved in this event are not well known. Herein, we performed comprehensive analyses on six ST3GAL family members, the α-2,3 sialyltransferases, in clear cell renal cell carcinoma (ccRCC) from public...

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Bibliographic Details
Main Authors: Jiakuan Liu, Meiqian Li, Jiajun Wu, Qi Qi, Yang Li, Simei Wang, Shengjie Liang, Yuqing Zhang, Zhitao Zhu, Ruimin Huang, Jun Yan, Rujian Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
sialylation
clear cell renal cell carcinoma
ST3GAL5
CD8+ T cell exhaustion
prognostic biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.979605/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.979605/full

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