17β-Estradiol Abrogates Oxidative Stress and Neuroinflammation after Cortical Stab Wound Injury

17β-Estradiol Abrogates Oxidative Stress and Neuroinflammation after Cortical Stab Wound Injury

Disruptions in brain energy metabolism, oxidative damage, and neuroinflammation are commonly seen in traumatic brain injury (TBI). Microglial activation is the hallmark of neuroinflammation. After brain injury, microglia also act as a double-edged sword with distinctive phenotypic changes. Therefore...

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Bibliographic Details
Main Authors: Kamran Saeed, Myeung Hoon Jo, Jun Sung Park, Sayed Ibrar Alam, Ibrahim Khan, Riaz Ahmad, Amjad Khan, Rahat Ullah, Myeong Ok Kim
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Antioxidants
Subjects:
traumatic brain injury
17β-estradiol
neuroprotection
oxidative stress
neuroinflammation
astrocytosis
Online Access:https://www.mdpi.com/2076-3921/10/11/1682

Internet

https://www.mdpi.com/2076-3921/10/11/1682

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