Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-α Overexpression in Sjögren’s Syndrome Patients

Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-α Overexpression in Sjögren’s Syndrome Patients

MicroRNAs (miRNAs) are small non-coding RNAs (sRNA), that alter gene expression by binding to target messenger RNAs (mRNAs) and repressing translation. Dysregulated miRNA expression has been implicated in the pathogenesis of autoimmune diseases such as Sjögren’s syndrome (SS). The aim of this study...

Full description

Bibliographic Details
Main Authors: Isabel Castro, Patricia Carvajal, Daniela Jara, Sergio Aguilera, Benjamín Heathcote, María-José Barrera, Víctor Aliaga-Tobar, Vinicius Maracaja-Coutinho, Ulises Urzúa, Andrew F. G. Quest, Sergio González, Claudio Molina, Marcela Hermoso, María-Julieta González
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
Sjögren’s syndrome
next generation sequencing
microRNA
hsa-miR-181d-5p
TNF-α
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.870094/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.870094/full

Similar Items