Complete genome sequencing of transposon-mediated sulfamethoxazole resistance encoded by the Sul1 gene in multidrug-resistant Nocardia farcinica SZ 1509

Complete genome sequencing of transposon-mediated sulfamethoxazole resistance encoded by the Sul1 gene in multidrug-resistant Nocardia farcinica SZ 1509

ABSTRACT: Objectives: The objective of this study is to explore the molecular basis of trimethoprim-sulfamethoxazole (SXT) resistance in Nocardia, an SXT-resistant N. farcinica strain, named SZ 1509, by whole-genome sequencing. Methods: Antimicrobial susceptibility testing of SZ 1509 was performed...

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Bibliographic Details
Main Authors: Yanlin Che, Shuai Xu, Yutong Kang, Xueping Liu, Yuan Yue, Lichao Han, Xiaotong Qiu, Dan Li, Yongliang Lou, Zhenjun Li
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Nocardia farcinica
Trimethoprim-sulfamethoxazole
Acquired resistance
sul1
Composite transposon
Complete genome sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S221371652200056X

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http://www.sciencedirect.com/science/article/pii/S221371652200056X

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