Inhibition of palmitoyl CoA deacylase by chlorophenoxyisobutyrate and betabenzalbutyrate

Palmitoyl CoA deacylase activity was measured in preparations of rat liver microsomes. Two hypolipidemic agents, chlorophenoxyisobutyrate and betabenzalbutyrate caused inhibition of palmitoyl CoA deacylase in vitro. The I50 values for chlorophenoxyisobutyrate and betabenzalbutyrate were 5.0 and 7.5...

Full description

Bibliographic Details
Main Authors: Robert G. Lamb, Patsy M. Hill, Harold J. Fallon
Format: Article
Language:English
Published: Elsevier 1973-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520368796