Case report: A case of metastatic BRAFV600-mutated melanoma with heart failure treated with immune checkpoint inhibitors and BRAF/MEK inhibitors

Case report: A case of metastatic BRAFV600-mutated melanoma with heart failure treated with immune checkpoint inhibitors and BRAF/MEK inhibitors

BackgroundNovel therapies, immune checkpoint inhibitors (ICIs), and BRAF/MEK inhibitors (BRAFi/MEKi) provide unprecedented survival benefits for patients with advanced melanoma. However, the management of drug-induced adverse events is problematic for both agents and, although rare, can cause seriou...

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Bibliographic Details
Main Authors: Aya Nishizawa, Misaki Kawakami, Yasuyuki Kitahara
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Oncology
Subjects:
metastatic malignant melanoma
BRAFV600 mutation-positive melanoma
immune checkpoint inhibitor
BRAF/MEK inhibitors
heart failure
COVID-19 vaccination
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1366532/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1366532/full

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