Structures of heat shock factor trimers bound to DNA

Structures of heat shock factor trimers bound to DNA

Summary: Heat shock factor 1 (HSF1) and 2 (HSF2) play distinct but overlapping regulatory roles in maintaining cellular proteostasis or mediating cell differentiation and development. Upon activation, both HSFs trimerize and bind to heat shock elements (HSEs) present in the promoter region of target...

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Bibliographic Details
Main Authors: Na Feng, Han Feng, Sheng Wang, Avinash S. Punekar, Rudolf Ladenstein, Da-Cheng Wang, Qinghua Zhang, Jingjin Ding, Wei Liu
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Molecular Structure
Structural biology
Protein structure aspects
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009196

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http://www.sciencedirect.com/science/article/pii/S2589004221009196

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