Unveiling the gut microbiota and metabolite profiles in guinea pigs with form deprivation myopia through 16S rRNA gene sequencing and untargeted metabolomics

Unveiling the gut microbiota and metabolite profiles in guinea pigs with form deprivation myopia through 16S rRNA gene sequencing and untargeted metabolomics

Aim: The aim of this study was to confirm the presence of the form deprivation myopia (FDM) guinea pig eye-gut axis and investigate the relationship between serum vasoactive intestinal peptide (VIP), lipopolysaccharides (LPS), specific gut microbiota and their metabolites. Method: 20 specific-pathog...

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Bibliographic Details
Main Authors: Yajun Wu, Hua Fan, Yuliang Feng, Jiasong Yang, Xiaobo Cen, Wensheng Li
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Heliyon
Subjects:
Form deprivation myopia
16S ribosomal RNA gene sequencing
Untargeted metabolomics
Gut microbiota
Metabolite
Vasoactive intestinal peptide
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024065228

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http://www.sciencedirect.com/science/article/pii/S2405844024065228

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