hMOF induces cisplatin resistance of ovarian cancer by regulating the stability and expression of MDM2

Abstract Histone acetyltransferase human males absent on the first (hMOF) is a member of MYST family which participates in posttranslational chromatin modification by controlling the acetylation level of histone H4K16. Abnormal activity of hMOF occurs in multiple cancers and biological alteration of...

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Bibliographic Details
Main Authors: Mingbo Cai, Sulong Xu, Yuxi Jin, Jingjing Yu, Shan Dai, Xiao-Jing Shi, Ruixia Guo
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01478-y