New insights into regulation of αIIbβ3 integrin signaling by filamin A

Abstract Background Filamin (FLN) regulates many cell functions through its scaffolding activity cross‐linking cytoskeleton and integrins. FLN was shown to inhibit integrin activity, but the exact mechanism remains unclear. Objectives The aim of this study was to evaluate the role of filamin A (FLNa...

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Bibliographic Details
Main Authors: Lamia Lamrani, Frédéric Adam, Christelle Soukaseum, Cécile V. Denis, Hana Raslova, Jean‐Philippe Rosa, Marijke Bryckaert
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Research and Practice in Thrombosis and Haemostasis
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Online Access:https://doi.org/10.1002/rth2.12672