Mechanotransduction Impairment in Primary Fibroblast Model of Krabbe Disease

Krabbe disease (KD) is a genetic disorder caused by the absence of the galactosylceramidase (GALC) functional enzyme. No cure is currently available. Here, we investigate the mechanotransduction process in primary fibroblasts collected from the twitcher mouse, a natural KD murine model. Thanks to me...

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書目詳細資料
Main Authors: Roberta Mezzena, Ambra Del Grosso, Roberto Maria Pellegrino, Husam B. R. Alabed, Carla Emiliani, Ilaria Tonazzini, Marco Cecchini
格式: Article
語言:English
出版: MDPI AG 2023-03-01
叢編:Biomedicines
主題:
在線閱讀:https://www.mdpi.com/2227-9059/11/3/927