Purine nucleotides reduce superoxide production by nitric oxide synthase in a murine sepsis model

Sepsis involves a systemic inflammatory response of multiple endogenous mediators, resulting in many of the injurious and sometimes fatal physiological symptoms of the disease. This systemic activation leads to a compromised vascular response and endothelial dysfunction. Purine nucleotides interact...

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Bibliographic Details
Main Authors: H.V. Barbeiro, D.F. Barbeiro, V. Debbas, H.P. Souza, F.R. Laurindo, I.T. Velasco, F.G. Soriano
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001100009