Ly6C(high) monocytes become alternatively activated macrophages in schistosome granulomas with help from CD4+ cells.

Ly6C(high) monocytes become alternatively activated macrophages in schistosome granulomas with help from CD4+ cells.

Alternatively activated macrophages (AAM) that accumulate during chronic T helper 2 inflammatory conditions may arise through proliferation of resident macrophages or recruitment of monocyte-derived cells. Liver granulomas that form around eggs of the helminth parasite Schistosoma mansoni require AA...

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Bibliographic Details
Main Authors: Natasha M Girgis, Uma Mahesh Gundra, Lauren N Ward, Mynthia Cabrera, Ute Frevert, P'ng Loke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4072804?pdf=render

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http://europepmc.org/articles/PMC4072804?pdf=render

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