Measurement of Aβ Amyloid Plaques and Tau Protein in Postmortem Human Alzheimer’s Disease Brain by Autoradiography Using [<sup>18</sup>F]Flotaza, [<sup>125</sup>I]IBETA, [<sup>124/125</sup>I]IPPI and Immunohistochemistry Analysis Using QuPath

Measurement of Aβ Amyloid Plaques and Tau Protein in Postmortem Human Alzheimer’s Disease Brain by Autoradiography Using [<sup>18</sup>F]Flotaza, [<sup>125</sup>I]IBETA, [<sup>124/125</sup>I]IPPI and Immunohistochemistry Analysis Using QuPath

High-resolution scans of immunohistochemical (IHC) stains of Alzheimer’s disease (AD) brain slices and radioligand autoradiography both provide information about the distribution of Aβ plaques and Tau, the two common proteinopathies in AD. Accurate assessment of the amount and regional location of A...

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Bibliographic Details
Main Authors: Rommani Mondal, Yasmin K. Sandhu, Vallabhi M. Kamalia, Brooke A. Delaney, Amina U. Syed, Grace A. H. Nguyen, Taylor R. Moran, Roz R. Limpengco, Christopher Liang, Jogeshwar Mukherjee
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
[<sup>18</sup>F]Flotaza
[<sup>125</sup>I]IPPI
[<sup>124</sup>I]IPPI
[<sup>125</sup>I]IBETA
Alzheimer’s disease
Aβ amyloid plaques
Online Access:https://www.mdpi.com/2227-9059/11/4/1033

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https://www.mdpi.com/2227-9059/11/4/1033

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