Immune Complex Vaccine Strategies to Combat HIV-1 and Other Infectious Diseases

Immune complexes (ICs) made of antibody-bound antigens exhibit immunomodulatory activities exploitable in a vaccination strategy to optimize vaccine efficacy. The modulatory effects of ICs are typically attributed to the Fc fragments of the antibody components, which engage Fc receptors, complement...

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Bibliographic Details
Main Authors: Alex F. Tang, Gospel Enyindah-Asonye, Catarina E. Hioe
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/9/2/112