Increased Tropism of Extracellular Vesicles Derived from Palmitic Acid-Treated Hepatocytes to Activated Hepatic Stellate Cells

Increased Tropism of Extracellular Vesicles Derived from Palmitic Acid-Treated Hepatocytes to Activated Hepatic Stellate Cells

Myofibroblast-like activated hepatic stellate cells (aHSCs), which produce collagen, a major cause of liver fibrosis, are specific target cells for antifibrotic treatment. Recently, several reports have indicated that extracellular vesicles (EVs) play important roles in cell-to-cell communication th...

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Bibliographic Details
Main Authors: Momoka Yamaguchi, Takanori Kanazawa, Sumire Morino, Shingo Iioka, Yuta Watanabe, Naoki Dohi, Kenjirou Higashi, Hiromu Kondo, Tomohisa Ishikawa
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Membranes
Subjects:
extracellular vesicles
liver fibrosis
hepatic stellate cells
hepatocytes
palmitic acid
drug delivery system
Online Access:https://www.mdpi.com/2077-0375/12/10/1023

Internet

https://www.mdpi.com/2077-0375/12/10/1023

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