WFS1 autosomal dominant variants linked with hearing loss: update on structural analysis and cochlear implant outcome

WFS1 autosomal dominant variants linked with hearing loss: update on structural analysis and cochlear implant outcome

Abstract Background Wolfram syndrome type 1 gene (WFS1), which encodes a transmembrane structural protein (wolframin), is essential for several biological processes, including proper inner ear function. Unlike the recessively inherited Wolfram syndrome, WFS1 heterozygous variants cause DFNA6/14/38 a...

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Bibliographic Details
Main Authors: Hui Dong Lim, So Min Lee, Ye Jin Yun, Dae Hee Lee, Jun Ho Lee, Seung-Ha Oh, Sang-Yeon Lee
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Medical Genomics
Subjects:
WFS1
DFNA6/14/38
Wolfram-like syndrome
Structure analysis
Cochlear implantation
Online Access:https://doi.org/10.1186/s12920-023-01506-x

Internet

https://doi.org/10.1186/s12920-023-01506-x

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