A novel chalcone derivative suppresses melanoma cell growth through targeting Fyn/Stat3 pathway

A novel chalcone derivative suppresses melanoma cell growth through targeting Fyn/Stat3 pathway

Abstract Background Fyn has been documented to have oncogenic features in multiple tumors, which might be a potential therapeutic target, however, few studies on the function role of Fyn and its specific inhibitors in melanoma. Methods We investigated the impacts of Fyn and its inhibitor Lj-1-60 on...

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Bibliographic Details
Main Authors: Ling Tang, Jing Long, Keke Li, Xu Zhang, Xiang Chen, Cong Peng
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Cancer Cell International
Subjects:
Melanoma
Chalcone derivative
Fyn
Stat3
Cell growth
Online Access:http://link.springer.com/article/10.1186/s12935-020-01336-2

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http://link.springer.com/article/10.1186/s12935-020-01336-2

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