LncRNA PCAT1 activates SOX2 and suppresses radioimmune responses via regulating cGAS/STING signalling in non‐small cell lung cancer

LncRNA PCAT1 activates SOX2 and suppresses radioimmune responses via regulating cGAS/STING signalling in non‐small cell lung cancer

Abstract Background The expression of long non‐coding RNA (lncRNA) prostate cancer‐associated ncRNA transcripts 1 (PCAT1) is increased in non‐small cell lung cancer (NSCLC). It stimulates tumour growth and metastasis, but its role in the radioimmune responses remain unknown. We aimed to explore the...

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Bibliographic Details
Main Authors: Yanping Gao, Nannan Zhang, Zihang Zeng, Qiuji Wu, Xueping Jiang, Shuying Li, Wenjie Sun, Jianguo Zhang, Yangyi Li, Jiali Li, Fajian He, Zhengrong Huang, Jinfang Zhang, Yan Gong, Conghua Xie
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Clinical and Translational Medicine
Subjects:
cGAS/STING
NSCLC
PCAT1
radioimmune responses
SOX2
Online Access:https://doi.org/10.1002/ctm2.792

Internet

https://doi.org/10.1002/ctm2.792

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