Impact of Reduced Cerebellar EAAT Expression on Purkinje Cell Firing Pattern of NPC1-deficient Mice
Abstract Niemann-Pick disease Type C1 (NPC1) is a rare hereditary neurodegenerative disease. NPC1-patients suffer, amongst others, from ataxia, based on a loss of cerebellar Purkinje cells (PCs). Impaired expression/function of excitatory amino acid transporters (EAATs) are suspected of contributing...
| Hauptverfasser: | , , , |
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| Format: | Artikel |
| Sprache: | English |
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Nature Portfolio
2018-02-01
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| Schriftenreihe: | Scientific Reports |
| Online Zugang: | https://doi.org/10.1038/s41598-018-21805-z |