Joint Transcriptome and Metabolome Analysis Prevails the Biological Mechanisms Underlying the Pro-Survival Fight in In Vitro Heat-Stressed Granulosa Cells

Joint Transcriptome and Metabolome Analysis Prevails the Biological Mechanisms Underlying the Pro-Survival Fight in In Vitro Heat-Stressed Granulosa Cells

Previous studies reported the physical, transcriptome, and metabolome changes in in vitro acute heat-stressed (38 °C versus 43 °C for 2 h) bovine granulosa cells. Granulosa cells exhibited transient proliferation senescence, oxidative stress, an increased rate of apoptosis, and a decline in steroido...

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Bibliographic Details
Main Authors: Abdul Sammad, Hanpeng Luo, Lirong Hu, Shanjiang Zhao, Jianfei Gong, Saqib Umer, Adnan Khan, Huabin Zhu, Yachun Wang
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biology
Subjects:
granulosa cells
heat stress
integrated analysis
genes
metabolites
protein metabolism
Online Access:https://www.mdpi.com/2079-7737/11/6/839

Internet

https://www.mdpi.com/2079-7737/11/6/839

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