Integrin beta1 (ITGB1) as a prognostic marker in esophageal adenocarcinoma

Abstract Today, individual prognosis in patients with adenocarcinoma of the esophagus (EAC) is based on post-surgical TNM staging and valid biomarkers are still not implemented. Integrin beta1 (ITGB1) is widely expressed in epithelial cells and promotes cell adhesion and growth. Its impact on tumor...

Full description

Bibliographic Details
Main Authors: Alexander I. Damanakis, Isabell Wahler, Hans Fuchs, Heike Löser, Wolfgang Schröder, Thomas Zander, Seung-Hun Chon, Christiane Bruns, Alexander Quaas, Florian Gebauer
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-25071-y