The somatic mutation landscape of the human body
Abstract Background Somatic mutations in healthy tissues contribute to aging, neurodegeneration, and cancer initiation, yet they remain largely uncharacterized. Results To gain a better understanding of the genome-wide distribution and functional impact of somatic mutations, we leverage the genomic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-12-01
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| Series: | Genome Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13059-019-1919-5 |