Differential expression of gene co-expression networks related to the mTOR signaling pathway in bipolar disorder

Abstract Bipolar disorder (BPD) is a severe mental illness characterized by episodes of depression and mania. To investigate the molecular mechanisms underlying the pathophysiology of bipolar disorder, we performed transcriptome studies using RNA-seq data from the prefrontal cortex (PFC) of individu...

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Bibliographic Details
Main Authors: Sung Woo Park, Mi Kyoung Seo, Maree J. Webster, Jung Goo Lee, Sanghyeon Kim
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01944-8