3D-QSAR Study of Combretastatin A-4 Analogs Based on Molecular Docking

Combretastatin A-4 (CA-4), its analogues and their excellent antitumoral and antivascular activities, have attracted considerable interest of medicinal chemists. In this article, a docking simulation was used to identify molecules having the same binding mode as the lead compound, and 3D-QSAR models...

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Bibliographic Details
Main Authors: Hongrui Song, Weige Zhang, Jian Wang, Qirong Shen, Zhiwei Wang, Ping Qi, Yinghua Jin
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/8/6684/