Free Fatty Acid Receptor 1 Signaling Contributes to Migration, MMP-9 Activity, and Expression of IL-8 Induced by Linoleic Acid in HaCaT Cells

Free Fatty Acid Receptor 1 Signaling Contributes to Migration, MMP-9 Activity, and Expression of IL-8 Induced by Linoleic Acid in HaCaT Cells

Keratinocytes and neutrophils are the main cellular components in wound healing during re-epithelization and inflammation. Free fatty acids such as linoleic acid (LA) present beneficial properties for wound healing by modulating the inflammatory response. LA is a natural ligand of free fatty acids r...

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Bibliographic Details
Main Authors: Carolina Manosalva, Pablo Alarcón, Karina González, Jorge Soto, Karin Igor, Fernanda Peña, Gustavo Medina, Rafael A. Burgos, María A. Hidalgo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
linoleic acid
free fatty acids receptor 1
keratinocytes (HaCaT)
neutrophils
migration
matrix metalloproteinase-9
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00595/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00595/full

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