Zn-Shik-PEG nanoparticles alleviate inflammation and multi-organ damage in sepsis

Zn-Shik-PEG nanoparticles alleviate inflammation and multi-organ damage in sepsis

Abstract Sepsis is defined as a life-threatening organ dysfunction caused by excessive formation of reactive oxygen species (ROS) and dysregulated inflammatory response. Previous studies have reported that shikonin (Shik) possess prominent anti-inflammatory and antioxidant effects and holds promise...

Full description

Bibliographic Details
Main Authors: Jie Guo, Yuqing Miao, Fayi Nie, Fei Gao, Hua Li, Yuan Wang, Qi Liu, Tingbin Zhang, Xiaohang Yang, Li Liu, Haiming Fan, Qiang Wang, Haifa Qiao
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Sepsis
Inflammatory
Shikonin
Reactive oxygen
Metal-polyphenol coordination
Online Access:https://doi.org/10.1186/s12951-023-02224-3

Internet

https://doi.org/10.1186/s12951-023-02224-3

Similar Items