Expression of Yarrowia lipolytica acetyl-CoA carboxylase in Saccharomyces cerevisiae and its effect on in-vivo accumulation of Malonyl-CoA

Expression of Yarrowia lipolytica acetyl-CoA carboxylase in Saccharomyces cerevisiae and its effect on in-vivo accumulation of Malonyl-CoA

Malonyl-CoA is an energy-rich molecule formed by the ATP-dependent carboxylation of acetyl coenzyme A catalyzed by acetyl-CoA carboxylase. This molecule is an important precursor for many biotechnologically interesting compounds such as flavonoids, polyketides, and fatty acids. The yeast Saccharomyc...

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Bibliographic Details
Main Authors: Humberto Pereira, Flávio Azevedo, Lucília Domingues, Björn Johansson
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Saccharomyces cerevisiae
ACC1
Fatty acids
Malonyl-CoA
Biosensor
Yarrowia lipolytica
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022000277

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http://www.sciencedirect.com/science/article/pii/S2001037022000277

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