Acamprosate reduces ethanol intake in the rat by a combined action of different drug components

Abstract Alcohol misuse accounts for a sizeable proportion of the global burden of disease, and Campral® (acamprosate; calcium-bis-(N-acetylhomotaurinate)) is widely used as relapse prevention therapy. The mechanism underlying its effect has in some studies been attributed to the calcium moiety and...

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Bibliographic Details
Main Authors: Karin Ademar, Anna Loftén, Mathilda Nilsson, Ana Domi, Louise Adermark, Bo Söderpalm, Mia Ericson
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45167-3