The Encapsulation of Citicoline within Solid Lipid Nanoparticles Enhances Its Capability to Counteract the 6-Hydroxydopamine-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells

The Encapsulation of Citicoline within Solid Lipid Nanoparticles Enhances Its Capability to Counteract the 6-Hydroxydopamine-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells

(1) Backgrond: Considering the positive effects of citicoline (CIT) in the management of some neurodegenerative diseases, the aim of this work was to develop CIT-Loaded Solid Lipid Nanoparticles (CIT-SLNs) for enhancing the therapeutic use of CIT in parkinsonian syndrome; (2) Methods: CIT-SLNs were...

Full description

Bibliographic Details
Main Authors: Andrea Margari, Anna Grazia Monteduro, Silvia Rizzato, Loredana Capobianco, Alessio Crestini, Roberto Rivabene, Paola Piscopo, Mara D’Onofrio, Valeria Manzini, Giuseppe Trapani, Alessandra Quarta, Giuseppe Maruccio, Carmelo Ventra, Luigi Lieto, Adriana Trapani
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
citicoline
solid lipid nanoparticles
6-hydroxydopamine
SH-SY5Y dopaminergic cells
Online Access:https://www.mdpi.com/1999-4923/14/9/1827

Internet

https://www.mdpi.com/1999-4923/14/9/1827

Similar Items