Simplified <sup>89</sup>Zr-Labeling Protocol of Oxine (8-Hydroxyquinoline) Enabling Prolonged Tracking of Liposome-Based Nanomedicines and Cells

Simplified <sup>89</sup>Zr-Labeling Protocol of Oxine (8-Hydroxyquinoline) Enabling Prolonged Tracking of Liposome-Based Nanomedicines and Cells

In this work, a method for the preparation of the highly lipophilic labeling synthon [<sup>89</sup>Zr]Zr(oxinate)<sub>4</sub> was optimized for the radiolabeling of liposomes and human induced pluripotent stem cells (hiPSCs). The aim was to establish a robust and reliable lab...

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Bibliographic Details
Main Authors: Andras Polyak, Jens P. Bankstahl, Karen F. W. Besecke, Constantin Hozsa, Wiebke Triebert, Rajeswara Rao Pannem, Felix Manstein, Thomas Borcholte, Marcus Furch, Robert Zweigerdt, Robert K. Gieseler, Frank M. Bengel, Tobias L. Ross
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
nanoparticles
liposomes
cell labeling
imaging
PET
nanomedicine
Online Access:https://www.mdpi.com/1999-4923/13/7/1097

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https://www.mdpi.com/1999-4923/13/7/1097

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