Cytotoxic mixed-ligand complexes of Cu(II): A combined experimental and computational study

Cytotoxic mixed-ligand complexes of Cu(II): A combined experimental and computational study

Herein, we report the synthesis of mixed-ligand Cu(II) complexes of metformin and ciprofloxacin drugs together with 1,10-phenanthroline as a co-ligand. The synthesized complexes were characterized using different spectroscopic and spectrometric techniques. In vitro cytotoxic activity against human b...

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Bibliographic Details
Main Authors: Mamaru Bitew Alem, Tadewos Damena, Tegene Desalegn, Moses Koobotse, Rajalakshmanan Eswaramoorthy, Kennedy J. Ngwira, Japheth O. Ombito, Matshediso Zachariah, Taye B. Demissie
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Chemistry
Subjects:
cytotoxicity
Cu(II) complexes
antibacterial activity
BOILED-egg
MCF-7
DFT
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.1028957/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.1028957/full

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