Single Cell Quantification of Reporter Gene Expression in Live Adult Caenorhabditis elegans Reveals Reproducible Cell-Specific Expression Patterns and Underlying Biological Variation.

In multicellular organisms such as Caenorhabditis elegans, differences in complex phenotypes such as lifespan correlate with the level of expression of particular engineered reporter genes. In single celled organisms, quantitative understanding of responses to extracellular signals and of cell-to-ce...

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Bibliografski detalji
Glavni autori: Alexander R Mendenhall, Patricia M Tedesco, Bryan Sands, Thomas E Johnson, Roger Brent
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2015-01-01
Serija:PLoS ONE
Online pristup:https://doi.org/10.1371/journal.pone.0124289