Mathematical model for assessing the level of cross-immunity between strains of influenza virus subtype H<sub>3</sub>N<sub>2</sub>

Mathematical model for assessing the level of cross-immunity between strains of influenza virus subtype H<sub>3</sub>N<sub>2</sub>

Introduction. The WHO regularly updates influenza vaccine recommendations to maximize their match with circulating strains. Nevertheless, the effectiveness of the influenza A vaccine, specifically its H3N2 component, has been low for several seasons. The aim of the study is to develop a mathemati...

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Main Authors: Marina N. Asatryan, Boris I. Timofeev, Ilya S. Shmyr, Karlen R. Khachatryan, Dmitrii N. Shcherbinin, Tatiana A. Timofeeva, Elita R. Gerasimuk, Vaagn G. Agasaryan, Ivan F. Ershov, Tatyana I. Shashkova, Olga L. Kardymon, Nikita V. Ivanisenko, Tatyana A. Semenenko, Boris S. Naroditsky, Denis Yu. Logunov, Aleksander L. Gintsburg
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2023-07-01
Series:Вопросы вирусологии
Subjects:
influenza virus
subtype h3n2
hai titers
cross-immunity
antigenic distance
antigenic site
hamming distance
regression analysis
epidemiological model
immune landscape
vaccine strain
Online Access:https://virusjour.crie.ru/jour/article/viewFile/12434/781

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https://virusjour.crie.ru/jour/article/viewFile/12434/781

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