Developments in zebrafish avatars as radiotherapy sensitivity reporters — towards personalized medicine

Background: Whereas the role of neoadjuvant radiotherapy in rectal cancer is well-established, the ability to discriminate between radioresistant and radiosensitive tumors before starting treatment is still a crucial unmet need. Here we aimed to develop an in vivo test to directly challenge living c...

Full description

Bibliographic Details
Main Authors: Bruna Costa, Susana Ferreira, Vanda Póvoa, Maria João Cardoso, Sandra Vieira, Joep Stroom, Paulo Fidalgo, Ricardo Rio-Tinto, Nuno Figueiredo, Oriol Parés, Carlo Greco, Miguel Godinho Ferreira, Rita Fior
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419307881