The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms
The research has been carried out with a focus on the assessment of the antimicrobial efficacy of pure nanohydroxyapatite, Cu<sup>2+</sup>-doped nanohydroxyapatite, ozonated olive oil-loaded nanohydroxyapatite, and Cu<sup>2+</sup>-doped nanohydroxyapatite, respectively. Their...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/10/10/1997 |
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| author | Wojciech Zakrzewski Maciej Dobrzynski Joanna Nowicka Magdalena Pajaczkowska Maria Szymonowicz Sara Targonska Paulina Sobierajska Katarzyna Wiglusz Wojciech Dobrzynski Adam Lubojanski Sebastian Fedorowicz Zbigniew Rybak Rafal J. Wiglusz |
| author_facet | Wojciech Zakrzewski Maciej Dobrzynski Joanna Nowicka Magdalena Pajaczkowska Maria Szymonowicz Sara Targonska Paulina Sobierajska Katarzyna Wiglusz Wojciech Dobrzynski Adam Lubojanski Sebastian Fedorowicz Zbigniew Rybak Rafal J. Wiglusz |
| author_sort | Wojciech Zakrzewski |
| collection | DOAJ |
| description | The research has been carried out with a focus on the assessment of the antimicrobial efficacy of pure nanohydroxyapatite, Cu<sup>2+</sup>-doped nanohydroxyapatite, ozonated olive oil-loaded nanohydroxyapatite, and Cu<sup>2+</sup>-doped nanohydroxyapatite, respectively. Their potential antimicrobial activity was investigated against <i>Streptococcus mutans, Lactobacillus rhamnosus</i>, and <i>Candida albicans</i>. Among all tested materials, the highest efficacy was observed in terms of ozonated olive oil. The studies were performed using an Ultraviolet–Visible spectrophotometry (UV-Vis), electron microscopy, and statistical methods, by determining the value of Colony-Forming Units (CFU/mL) and Minimal Inhibitory Concentration (MIC). |
| first_indexed | 2024-03-10T15:44:30Z |
| format | Article |
| id | doaj.art-8aaf1ecb9ab64de3a7d833d246ba7cc5 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T15:44:30Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-8aaf1ecb9ab64de3a7d833d246ba7cc52023-11-20T16:32:52ZengMDPI AGNanomaterials2079-49912020-10-011010199710.3390/nano10101997The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of MicroorganismsWojciech Zakrzewski0Maciej Dobrzynski1Joanna Nowicka2Magdalena Pajaczkowska3Maria Szymonowicz4Sara Targonska5Paulina Sobierajska6Katarzyna Wiglusz7Wojciech Dobrzynski8Adam Lubojanski9Sebastian Fedorowicz10Zbigniew Rybak11Rafal J. Wiglusz12Department of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, PolandDepartment of Conservative Dentistry and Pedodontics, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, PolandDepartment of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, PolandDepartment of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, PolandDepartment of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, PolandInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, PolandInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, PolandDepartment of Analytical Chemistry, Wroclaw Medical University, Borowska 211 A, 50-566 Wroclaw, PolandStudent Scientific Circle at the Department of Dental Materials, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Akademicki Sq. 17, 41-902 Bytom, PolandDepartment of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, PolandDepartment of Microbiology, Wroclaw Medical University, Chalubinskiego 4, 50-368 Wroclaw, PolandDepartment of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-345 Wroclaw, PolandInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, PolandThe research has been carried out with a focus on the assessment of the antimicrobial efficacy of pure nanohydroxyapatite, Cu<sup>2+</sup>-doped nanohydroxyapatite, ozonated olive oil-loaded nanohydroxyapatite, and Cu<sup>2+</sup>-doped nanohydroxyapatite, respectively. Their potential antimicrobial activity was investigated against <i>Streptococcus mutans, Lactobacillus rhamnosus</i>, and <i>Candida albicans</i>. Among all tested materials, the highest efficacy was observed in terms of ozonated olive oil. The studies were performed using an Ultraviolet–Visible spectrophotometry (UV-Vis), electron microscopy, and statistical methods, by determining the value of Colony-Forming Units (CFU/mL) and Minimal Inhibitory Concentration (MIC).https://www.mdpi.com/2079-4991/10/10/1997Cu<sup>2+</sup> ionsozonated olive oilhydroxyapatiteantimicrobial activitymicroorganisms |
| spellingShingle | Wojciech Zakrzewski Maciej Dobrzynski Joanna Nowicka Magdalena Pajaczkowska Maria Szymonowicz Sara Targonska Paulina Sobierajska Katarzyna Wiglusz Wojciech Dobrzynski Adam Lubojanski Sebastian Fedorowicz Zbigniew Rybak Rafal J. Wiglusz The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms Nanomaterials Cu<sup>2+</sup> ions ozonated olive oil hydroxyapatite antimicrobial activity microorganisms |
| title | The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms |
| title_full | The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms |
| title_fullStr | The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms |
| title_full_unstemmed | The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms |
| title_short | The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms |
| title_sort | influence of ozonated olive oil loaded and copper doped nanohydroxyapatites on planktonic forms of microorganisms |
| topic | Cu<sup>2+</sup> ions ozonated olive oil hydroxyapatite antimicrobial activity microorganisms |
| url | https://www.mdpi.com/2079-4991/10/10/1997 |
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